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Common qualitative changes after pharmaceutical absorb moisture? Which medicines are more susceptible to moisture?

Source:Editor:PV:-Date:2020-11-25 11:25【L M S

  Humidity, temperature, light and other factors can all promote the deterioration and failure of medicines. Among all the factors, humidity has the most serious impact on medicines.

  The following qualitative changes often occur after drugs pharmaceutical absorb moisture

  1. Discoloration: The qualitative change phenomenon of oxidation and discoloration occurs easily when the medicine is damp. The color becomes darker, from white to yellow or other colors. After discoloration, the medicine may have increased toxicity or decreased potency and thus become invalid.

  2. Melting adhesion: Hygroscopic tablets will melt adhesion after absorbing moisture.

  3. Softening: The shell of the capsules is mainly made of gelatin, which will soften when it gets wet.

  4. Mildew: Improper storage of medicines, mold will quickly grow and multiply in a warm and humid environment.

  5. Splinters and loose slices: some tablets will swell when damp, which can cause splinters and loose slices.

  6. Precipitation of crystals and volatilization: improper storage of medicines will easily decompose and precipitate crystals after being damp, and produce volatilization phenomena after heating.

  The following types of medicines are more susceptible to moisture

  1. Granules and granules

  This kind of medicine is a dry granular (or block) oral preparation made from fine powder or extract of medicine with auxiliary materials such as powdered sugar. This kind of medicine is easy to deliquesce and agglomerate in a humid environment.

  2. Powder

  Powder is a powdery preparation made by uniformly mixing one or more drugs. Since the surface area of the powder is larger than that of other dosage forms, its hygroscopicity is more remarkable.

  3. Effervescent tablets

  The effervescent tablet is a dosage form of medicine added with solubilizing ingredients in its production, so it will generate gas when it encounters water, causing the effervescent tablet to swell, deform, and rupture, so it is very easy to deliquesce and deteriorate.

  4. Chinese herbal medicine

  Traditional Chinese medicinal materials generally do not have special packaging. If they are not stored properly, they are more prone to mildew, moth-eaten, discoloration, and oily phenomena, leading to deterioration.

  Chunwang pharmaceutical Desiccant can effectively solve the above problems.